Research led by the ICAHN College of Medicine, which was funded by the National Cancer Institute (National Cancer Institute) with the Federation of Clinical Protein Tumor Analysis (CPTAC), has reached the conclusion.
Our genetic differences play with us a much greater role in the development and behavior of oncology than we thought before.
Fotó: 3dedisphere / Science Photo Libra / SKX
A cell It was published in its number on the Internet on April 14 Ticket This is the first to show how millions of hereditary genetic differences in people affect the work of thousands of cancer cell proteins. A study of more than 1,000 patients, which contain ten different types of cancer, displays how unique genetic properties for each person form the biological behavior of the tumor there.
Results can reshape the future medical treatment of cancer. While current treatments take into account the genetic properties of the tumor, recent research indicates that the examination of the inherited genetic variables of the patient can increase the clarification of diagnosis, evaluation of risk and the choice of appropriate treatment.
Treatment of allocated cancer is the key to healing
“Everyone has a unique mixture of genetic variables from birth, and these inherited differences are unobtrusive to our cells throughout our lives,” explains Zeynep H. Gümüş, professor of genetics and genetic science at Mount Sinai ICahn Medicine College. They sit in the background, but they play an active role in the development and development of tumors, and even in the way the tumors respond to treatments.
This opens new opportunities to customize cancer treatment, which can now take into account not only the tumor itself, but also the congenital genetic properties of the patient. “
To date, the majority of tumors related to physical, therefore. Focus on the physical mutations that occur during the life of this person in his cells. However, we carry more than a genetic and more heavy version than the physical boom, and so far we have not known much about their role in cancer, as the authors emphasize.
