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Index – Science – Why dieting is useless? Because genes are like that!

Index – Science – Why dieting is useless?  Because genes are like that!

In a New York Post article We can read, that the tendency to regularly eat high-calorie foods is not due to the taste or smell of the food. Although chips or hamburgers are delicious, we don’t throw ourselves at them in the same way. Why?

This is because the gene responsible for overeating does not work well for everyone, and if it malfunctions, we will go on a completely unnecessary diet. We can feel a great sense of relief, since it is not we who are weak-willed, but our genes that force us to lose weight, but this does not mean that we have to put up with the situation.

Researchers at Japan’s Osaka Metropolitan University found that the CREB-regulated Coactivator 1 (CRTC1) gene can limit overeating, especially when it comes to fast food. Professor Seiginobu Matsumura led the research team that investigated the anti-obesity function of CRTC1. The researchers focused on neurons that express melanocortin 4 (MC4R), which plays an important role in the body. of his energy in its maintenance.

According to studies, CRTC1 in MC4R-expressing neurons will prevent obesity. In the rat experiments, the researchers divided the animals into two groups, one with the CRTC1 gene, and the other without. In mice lacking the gene, a high-calorie diet led to overeating, diabetes, and obesity.

The study revealed that the CRTC1 gene plays an important role in not eating too many high-calorie, fatty and sugary foods.

Segenobu Matsumura said.

People who have a genetic variant of CRTC1 or have a dysfunctional one are more likely to be obese than people who have a normally functioning gene.

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(Cover photo: Billy and Penny McCrary, the world’s oldest twins, in Hendersonville on November 25, 1969. Photo: Bettmann/Getty Images)