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Index – Science – It’s not a fairy tale if we always live in the same day

Index – Science – It’s not a fairy tale if we always live in the same day

We still remember 1993 From time immemorial To the Bill Murray comedy, in which a sarcastic, always-weary protagonist goes through the same day, starting on Sonny & Cher’s note? Well, this is a standing issue, a state of “déja vécu”, which is similar to deja vu, but the focus is not on seeing, but on experiencing. The patient feels that he is going through the same things over and over again. A strange experience may be a rare complication of Alzheimer’s disease.

Just a fleeting feeling

In neurodegenerative diseases, cells of the central nervous system shut down and eventually die. Deja vu describes a fleeting feeling, trigger her It can be stress, fatigue, and even epilepsy. Déjà vico is the constant perception that new encounters are repetitions of past experiences.

With déjà vu, we realize that the experience is not real, but with déjà vécu, that is not.

People who suffer from this often They do not knowThey are ill and develop false beliefs and delusion-like behaviors that justify their abnormal perception. False perception and (the brain) producing unrealistic evidence to support it is called Confabulation. Not joking, as one of his tormentors said:

Everywhere I go I see the same people, the same cars behind me, the same people getting out of them, the same clothes, the same bags, everyone saying the same thing, nothing new.

This phenomenon, abbreviated as DVRC, has been described in a few other patients with neurodegeneration, including some Alzheimer’s patients. The cause is unknown, but according to some assumptions, it is a dysfunction of the hippocampus, which helps to convert short-term memories into long-term memories, and thus wrong memory can lead.

A disoriented, amnesiac man who often confuses the events of his life was found to have impulsive behavior and cognitive decline, and when his brain was examined, they noted reduced activity in the left temporal lobe and frontal lobe. When analyzing the spinal cord and cerebrospinal fluid, they found that the level of the amyloid beta-42 protein decreased, but that of the tau protein increased. These are clear signs of Alzheimer’s disease.

He was treated with immunotherapy, and his condition improved, but four years after the onset of symptoms, his cognitive abilities were worse.

In the largest DVRC case file, 13 patients were reported, including nine with probable Alzheimer’s disease, three with mild cognitive impairment, and one with frontotemporal dementia. This is the first DVRC report that uses scans to analyze brain activity, examine cerebrospinal fluid, and perform neuropsychological mapping. Fortunately, unlike deja vu, which only lasts 10 to 30 seconds and usually strikes us in the evening when we’re tired or stressed, deja vécu can be checked because it’s not a temporary experience.